For a while there was Goodwill, but it's long been gone. We still do have the Salvation Army store, and there is a Value Village, but Value Village is not what I'd call a "thrift" store any longer.
This is a list of thrift stores and second hand stores that not only provide decent value, but many of whom also use their funds to support local charity groups so the money tends to stay "in town". If the store has it's own website or social site page, I've linked to that so you can contact them if you require.
Salvation Army Thrift Store
55 Wyandotte St, Orillia
Mon-Sat
Second Chance Thrift Store
($2 clothing)
117 Atherley Rd (Atherley & Gill)
Orillia Thrift Store
10 Western Ave
Mon to Wed 10am to 3pm
Thursday 10am to 5pm
Fri and Sat 10am to 3pm
Pennywise Thrift Shop
St. James Church
(Peter St. - entry at back of church (down the stairs)
Tues-Thursday 12 to 3pm
Saturday 10 to 2 pm
Vinnies Clothing Thrift Store
Guardian Angels Parish, Orillia
Mississaga St. Open Tuesdays & Thursdays 1-3pm
Throughout the year some of the other churches have sales that included used clothing as well as other goods - they're often found listed under the Garage Sale section of Orillia Matters and on social type sites. Those you generally have to look for, but they often turn up some pretty fun shopping opportunities.
These next 2 stores are not really what I'd call "thrift" stores. Although Habitat does support charity, I haven't honestly found them as useful for household items - mostly some furniture and home repair items. I also find them a little overpriced for the item quality (not always, but most times I've been in, I've left empty handed).
Habitat for Humanity ReStore
James St West
Value Village
Westridge Plaza
This last one isn't really a "thrift" store, although you can find some good buys here since it's a consignment shop geared towards kids clothing located on the main street of Orillia. I wrote about this one in a blog post, so you can find more in this article:
Coach House Kids
gently used kids clothes